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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Partial cloning ： ウィキペディア英語版 Partial cloning In the field of cell biology, the method of partial cloning (PCL) converts a fully differentiated ''old'' somatic cell into a partially reprogrammed ''young'' cell that retains all the specialised functions of the differentiated ''old'' cell but is simply younger. The method of PCL reverses characteristics associated with old cells. For example old, senescent, cells ''rejuvenated'' by PCL are free of highly-condensed senescence-associated heterochromatin foci (SAHF) and re-acquire the proliferation potential of young cells. The method of PCL thus rejuvenates old cells without de-differentiation and passage through an embryonic, pluripotent, stage. == Method == PCL consists in introducing a somatic adult or senescent cell nucleus or entire cell with enlarged membrane pores in an (activated) oocyte and to withdraw this treated cell before its de-differentiation and first cell division occurs. Thus, the progressive rejuvenation capability of the oocyte is used only temporarily in order to obtain a partial natural rejuvenation. PCL permits to envisage a chosen degree of partial rejuvenation in changing the duration of the introduction of the treated cell in the oocyte. Using PCL cell de-differentiation and its age reprogramming might be, at least partially, separable. Thus the existence of an isolated ageing clock would be confirmed at least during a certain part of the cellular evolution and involution. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Partial cloning」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.